Best Mouse for Wrist Pain – Our Top 7 Picks

#1 Pick

Anker 2.4G Wireless Vertical Ergonomic Optical Mouse


Logitech MX Master 3 Advanced Wireless Mouse

Best Budget

iClever Vertical Mouse

Are you a major gamer who spends most of your time on the computer? Or, do you use who uses a computer mouse a lot because of your work?Do you sense a pinching pain in your wrist after long hours of holding the mouse? Then you probably need to get a new one.  

People who spend hours on the computer either for gaming or other tasks need a properly designed mouse, keyboard, and seating arrangement. Investing in your comfort will ensure a good and healthy quality of life. 

Working with a mouse puts a lot of pressure on the wrist, which can cause pain and discomfort. If you are using a conventional mouse, you can even develop Carpal Tunnel Syndrome. Meanwhile, a good ergonomic mouse can alleviate some of that pressure and save you from wrist pain.

With the prevalence of wrist pain in mind, we have searched the market for the best mice to increase your comfort levels when working or playing on the computer. 

Best Mice for Wrist Pain

If you are struggling to find the right mouse that won’t strain your wrists, we have got you covered. Check out our list of the 7 best mice for wrist pain. Let’s dive in!

#1 Pick

Anker 2.4G Wireless Vertical Ergonomic Optical Mouse
Anker 2.4G Wireless Vertical Ergonomic Optical Mouse
Score 8.6OUT OF 10

Logitech MX Master 3 Advanced Wireless Mouse
 Logitech MX Master 3 Advanced Wireless Mouse
Score 9.2OUT OF 10
Best Budget

iClever Vertical Mouse
iClever Vertical Mouse
Score 8.8OUT OF 10
LEKVEY Vertical Wireless Mouse
LEKVEY Vertical Wireless Mouse
Score 8.6 OUT OF 10
SANWA 2.4G Wireless Ergonomic Trackball Mouse
SANWA 2.4G Wireless Ergonomic Trackball Mouse
Score 8.2OUT OF 10
AUTLEY Wireless Ergonomic Mouse
AUTLEY Wireless Ergonomic Mouse
Score 8.4OUT OF 10
Wireless Mouse 2.4G Ergonomic Vertical Optical Mouse
Wireless Mouse 2.4G Ergonomic Vertical Optical Mouse
Score 8.2OUT OF 10

1. Logitech M570 Wireless Trackball Mouse

Score 8.6 OUT OF 10
Anker 2.4G Wireless Vertical Ergonomic Optical Mouse

Anker is a renowned brand that produces intelligent devices such as chargers, speakers, mouses, keyboards, and many other products. All their products have earned much respect for being valuable and durable at the same time. The wireless ergonomic mouse by Anker is an incredible product that ensures the reduction of strain on the arms.

This impeccable mouse introduced by Anker has sighed relief to all the pro gamers. The mouse is scientifically designed to minimize the overall strain on the arm and wrist. It features a neutral arm position for smooth movements.

The mouse is compact. Another good thing about the mouse is that it is wireless, so you do not need to tackle the annoying cables.  

The mouse allows you to adjust the mouse sensitivity according to your preference. There are three levels of sensitivity: 800, 1200, 1600DPI. The design and functionality of the mouse are highly advanced for all kinds of gaming purposes. 

The mouse has five buttons that allow complete access to your computer system. The buttons are sufficient for your gaming needs through which you can perform multiple functions at a time. 

The mouse is compatible with many computer systems, including Windows Vista, XP, 2000, Linux, 7, 8, and 10. Some features of the mouse are also compatible with Mac OS X.


  • Functional design
  • Reasonably priced

  • It is not an anti-slip mouse
  • It lacks pinky finger rest

2. Logitech MX Master 3 Advanced Wireless Mouse

Score 9.2 OUT OF 10
 Logitech MX Master 3 Advanced Wireless Mouse

Logitech is constantly introducing products that make working from home more accessible. They make keyboards, mice, speakers, and much more. All of their creations feature minimal designs with high-level functionality.

Their products are equally great for gamers as they enhance the comfort and efficiency of the player. 

The MX Master three advanced wireless mouse is an incredible invention for gaming freaks as it is an ergonomic mouse. The ergonomic design of this mouse lessens the stress on the wrist. Due to reduced strain on the arm, it quickly becomes the favorite mouse of every gamer. 

This mouse allows you ultra-fast scrolling with high precision, which means you can scroll 1000 lines within a second. There are plenty of customization options that you can control from the app and use the mouse according to your requirements. 

It is a rechargeable mouse. The charging system is pretty quick as a one-minute charge gives three hours of use. Once the mouse is fully charged, it will last more than 70 days. 

There are highly efficient sensors with excellent resolution, like 4000 DPI. The mouse works equally great on all surfaces, including glass. What’s more, it is also compatible with all kinds of computer software such as Windows, Mac, or Linux. 

All-in-all this mouse by Logitech is an excellent option for people with long working hours or gaming sessions.


  • Outstanding battery life
  • Compatible with a variety of software 
  • Lightweight

  • The manual scroll wheel function does not work
  • Expensive mouse

3. IClever Vertical Mouse

Score 8.8 OUT OF 10
iClever Vertical Mouse

iClever is a famous brand of electronic products, founded in 2010. It uses modern technology to enhance intelligent living opportunities and inspire users to move faster. Due to their dedication and innovation, tech geeks around the world have always appreciated their products.

Like their other products, their vertical mouses have gained massive popularity across the globe because they have all the features one desires. Many professional gamers, tech geeks, and freelancers prefer iClever mouses due to their many attractive features.

If you are tired of using your uncomfortably tiny mouses, take a break and try this ergonomic mouse of iClever. This 2.4G Wireless Vertical Ergonomic Mouse is a solution if you face wrist pain issues during your long gaming sessions. 

This mouse has an unconventional grip and is specially designed for your ultimate comfort. The combination of class, comfort, and functioning make this mouse one of the best choices in the 21st century.

An optical sensor of 2400 DPI ensures the most delicate movements with minimum effort. It carefully calculates weight, stability, and control on almost any surface. The power of this mouse is precise to a professional level. Depending on your needs, you can adjust it between four resolutions of 1000 DPI, 1600 DPI, 2000 DPI, and 2400 DPI. 

Since this mouse is wireless, you can use it anywhere and everywhere. It has an auto power-saving feature that turns the mouse after 10 minutes of inactivity. This incredible mouse offers compatibility with a wide variety of software, including Apple products. 

This highly functional and easy-to-use mouse is a perfect option for a person who has long working hours. This mouse will indeed become your best friend if you suffer from wrist pain.  


  • High sensitivity
  • Noiseless buttons
  • Smooth and comfortable usage

  • Scrolling malfunction occurs
  • It is not a good people with small hands

4. LEKVEY Vertical Wireless Mouse

Score 8.6 OUT OF 10
LEKVEY Vertical Wireless Mouse

Lekvey is a well-known brand for creating easy-to-use and innovative accessories. Their products promote comfort and quality at the same time. Lekvey keeps introducing new developments in the market specifically designed for people who love gaming a bit too much. All their products are equally great for people with long working hours at the office as well.

The vertical ergonomic mouse by Lekvey is another fantastic invention that is a sigh of relief for people with wrist pain or carpal tunnel syndrome. The shape of this mouse is helpful for such people because it reduces the strain or stress on the arm. 

There are six buttons on the mouse that perform different functions for a smooth user experience. It is a rechargeable mouse, so you do not need to change batteries often. A charging cable comes with a mouse that you can use for quickly charging the mouse. 

The mouse allows you to adjust the sensitivity according to your level of the task. There are three options of sensitivity: 800, 1200, 1600 DPI. The mouse is widely compatible with various software except for Mac OS, apple products. 

Another good thing about getting this mouse is the excellent customer service by Lekvey. They believe in the high quality of their product. Hence, they provide an 18 monthly warranty with their products. So, if you ever have problems with the mouse, you can replace or refund it. 

This vertical wireless mouse by Lekvey is genuinely a dream come true for pro gamers.


  • Six useful buttons
  • Excellent for wrist pain
  • It gets fully charged quickly

  • Shuts off after inactivity of less than 1 minute
  • Battery life is not great

5. SANWA 2.4G Wireless Ergonomic Trackball Mouse

Score 8.2 OUT OF 10
SANWA 2.4G Wireless Ergonomic Trackball Mouse

Since 1923, SANWA has had a long history of producing computer accessories. It is a Japanese brand that takes pride in providing impeccable customer service. All the products by SANWA represent uniqueness and versatility. They are available almost throughout the world and successfully meet the expectations of their customers.

The 2.4G wireless ergonomic trackball mouse by SANWA is a must-have device for people who work for long hours or are regular gamers. The mouse’s ergonomic design allows a natural hand position to lower the strain on the wrist and arm. It provides comfortable thumb and finger rest to ensure smooth usage. 

The mouse features a 34mm trackball that you can control with your thumb to quickly move the cursor. The trackball enhances the usability of the mouse. 

There are noiseless buttons on the mouse so that you can use it in public places as well. The sensitivity of the mouse is adjustable. There are four levels for sensitivity that you can choose from: 600, 800, 1200, 1600 DPI. 

The mouse is widely compatible with various software. However, it is not entirely compatible with Apple products. So, if you have an Apple PC, then you should consider some other options. 

Overall, it is an incredible choice because it is easy to use and reduces the risk of wrist pain.


  • Buttons are noiseless
  • Good options for sensitivity

  • The trackball is not very smooth
  • It is not compatible with Apple products

6. AUTLEY Wireless Ergonomic Mouse

Score 8.4 OUT OF 10
AUTLEY Wireless Ergonomic Mouse

AUTLEY creates innovative computer accessories for enhanced user experience. They are mostly known for their vast collection of mice that perform pretty well in functionality and durability. Their creative and innovative designs assure the comfort of users.

The wireless ergonomic mouse by AUTLEY is one of their commendable devices. This mouse is perfect for people with significant and broad hands because it is a giant mouse. The ergonomic design keeps your hand in its natural position without putting extra tension on the arm. 

The mouse has a matte coating on its exterior that ensures a comfortable and anti-slip touch. It feels great in the hands. There is a fancy blue light in the mouse, which you can switch on or off with a button. 

It contains a rechargeable battery that takes almost two hours to be fully charged. The fully charged mouse lasts 12-20 days. You can even use the mouse while it is on charging. 

There are three levels of sensitivity that you can adjust according to your needs. You can switch 800, 1200, 1600 DPI levels with the DPI button. 

Additionally, the customer service of AUTLEY is the highlight of this mouse because they provide a 90 days money-back guarantee. You also get a 1-year replacement service which is incredible. 

So, even if you are not sure about this mouse, you can still give it a try. If you do not like it, return it and get your money back.


  • Great for wrist pain
  • Fast charging
  • It fits nicely in medium-sized hands

  • It does not work well on a glass surface
  • The scroll messes up sometimes

7. TECKNET Pro 2.4G Wireless Mouse

Score 8.2 OUT OF 10
Wireless Mouse 2.4G Ergonomic Vertical Optical Mouse

Next on our list is the wireless ergonomic mouse by Viwind. This highly functional and elegant design is one of its kind. It comes in fun and vibrant colors that are appealing to the eyes. This sturdy mouse enables a neutral hand position by minimizing overall strain on the arm.

The mouse has a smooth and sweat-proof finish that prevents fingers from sliding. It is comfortable to hold for more extended periods. 

The mouse features a built-in rechargeable 650mA battery. It charges pretty quickly. After a complete charging of three hours, you can use the mouse for 720 hours. It has an auto-sleep feature, meaning the power saving mode turns on automatically when the mouse remains idle for eight minutes. 

There are four adjustable DPI levels: 800, 1200, 1600, 2400. You can easily change the levels to increase or decrease cursor sensitivity. This mouse certainly provides higher precision. 

It is compatible with many software, including Windows, Linux, and Mac OS X. This mouse is a great overall option as an affordable and stylish-looking mouse.


  • Available in fun colors
  • Works wonders for wrist pain
  • Extremely affordable

  • Requires a mousepad while using
  • The scroll wheel gets stuck

Buying Guide

Every day, brands are introducing innovative products to make our lives a little easier. They are in a constant race to launch the most unique and valuable products that customers will love. 

Computer mice are no exception. However, this wide variety of mice makes it challenging, if not downright frustrating, to decide on the best product for yourself. So, here are a few essential features to look for in a mouse to prevent wrist pain. 

Ergonomic Design

Ergonomically designed mice are different from conventional ones. They are specifically designed to take the pressure off your wrist and arm. All your fingers will rest comfortably on the mouse, and you will not have to strain your wrist. 


To avoid dealing with annoying wires, we recommend opting for a wireless mouse. This will also reduce the clutter on your, creating a more pleasant work environment.  


We don’t recommend a battery-operated mouse when choosing a mouse because you will constantly have to change the batteries. It is better to get a rechargeable mouse, as they have an excellent battery life that can last you days. 

Higher Sensitivity

A good mouse has various options to adjust its sensitivity. A mouse with a higher DPI  has higher sensitivity. This results in increased precision, which is perfect for gamers who enjoy shooting games and for graphic designers and illustrators. So, make sure the mouse has good and adjustable sensitivity. 


1. What is DPI, and how does it affect mouse precision?

DPI (dots per inch) refers to how a mouse measures distance. The DPI number represents the level of sensitivity of the mouse and the speed of the pointer. The higher DPI means that the mouse has a more precise performance. 

2. Why does a conventional mouse cause wrist pain? 

A conventional mouse puts a lot of pressure on the thumb, fingers, wrist, and arm. The constant tension placed on these areas results in wrist pain, which can lead to Carpal Tunnel Syndrome. 

So, it is better to ditch the conventional mouse and go for an ergonomically designed one instead. The investment in your health and personal comfort will serve you well in the long run. 

3. Is an ergonomic mouse good for gaming? 

Pro gamers – or even regular gamers – usually spend hours in front of their computers. Using a conventional mouse for prolonged hours of intense gaming can lead to discomfort and wrist pain. 

Over time their performance might suffer. That is why it is far better for gamers to take care of their health and use a vertical ergonomic mouse. The switch ensures that they keep playing painlessly for years to come.

4. Are battery-operated mice better than rechargeable mice? 

Battery-operated mice cause problems because you have to keep changing the batteries every once in a while. However, a rechargeable mouse can last you up to several days once it is fully charged. We recommend charging it overnight so the battery does not accidentally die in the middle of your work. 


Whether you are a gamer or a professional who spends hours working on your computer, you likely deal with occasional or persistent wrist pain. Either way, you need to replace your conventional mouse because that is what is causing your wrist pain. Get yourself an excellent ergonomic mouse to transform your entire experience. 

An ergonomic mouse maintains the hand in a natural position and allows all the fingers to rest correctly. This ensures that you don’t strain your wrist and can comfortably use the mouse for hours. 

However, it can be overwhelming to select one mouse from all the available options. Our list of the 7 best mice for wrist pain will help you make sense of all the options and find the one that is best suited to your needs. We guarantee it will be one of the best decisions you make!

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